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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM126B
All Species:
20.91
Human Site:
T448
Identified Species:
46
UniProt:
Q8IXS8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXS8
NP_776183.1
530
58647
T448
N
S
L
S
L
I
R
T
A
S
A
S
S
S
K
Chimpanzee
Pan troglodytes
XP_516024
586
64532
T504
N
S
L
S
L
I
R
T
A
S
A
S
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001094374
586
64520
T504
N
S
L
S
L
I
R
T
A
S
A
S
S
S
K
Dog
Lupus familis
XP_545590
529
58664
T447
N
S
L
S
L
I
R
T
A
S
A
S
S
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C729
530
58568
T448
N
S
L
S
L
I
R
T
A
S
A
S
S
S
K
Rat
Rattus norvegicus
NP_001020881
456
50806
K377
S
Q
R
G
S
L
R
K
V
A
T
G
R
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513800
607
67012
P525
T
S
Q
S
L
P
K
P
G
S
H
S
L
A
R
Chicken
Gallus gallus
Q5ZM13
515
57202
G435
S
Q
S
L
P
K
P
G
S
H
S
L
A
R
T
Frog
Xenopus laevis
NP_001090270
408
45485
W329
M
S
I
R
G
H
R
W
K
R
H
E
E
P
D
Zebra Danio
Brachydanio rerio
Q6P121
518
56409
L434
L
S
L
K
R
L
T
L
T
A
S
Q
S
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624097
512
56909
S433
S
K
E
N
I
K
G
S
S
S
M
L
N
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.4
90.2
97.1
N.A.
95.2
82.4
N.A.
46.2
53.2
45.8
49.2
N.A.
N.A.
27.1
N.A.
N.A.
Protein Similarity:
100
90.4
90.2
98.6
N.A.
97.3
84.5
N.A.
60.7
68.6
60
68.4
N.A.
N.A.
52.6
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
33.3
0
13.3
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
53.3
26.6
20
40
N.A.
N.A.
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
46
19
46
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
10
10
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
10
19
0
0
0
0
% H
% Ile:
0
0
10
0
10
46
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
19
10
10
10
0
0
0
0
0
46
% K
% Leu:
10
0
55
10
55
19
0
10
0
0
0
19
10
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
46
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
10
10
10
10
0
0
0
0
0
10
10
% P
% Gln:
0
19
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
10
10
0
64
0
0
10
0
0
10
10
10
% R
% Ser:
28
73
10
55
10
0
0
10
19
64
19
55
55
64
0
% S
% Thr:
10
0
0
0
0
0
10
46
10
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _